Organ / Tissue Donation and Transplantation

When a person wants to donate a kidney to someone they know, but medical tests indicate the donor and recipient are not suitable matches, the person needing the kidney transplant and the incompatible donor can enrol in the Living Donor Paired Exchange (LDPE) together as an incompatible pair. If the LDPE can find a match for both the donor and the recipient, the donor donates to an unknown recipient so that donor’s recipient can receive a kidney from someone else’s incompatible donor.

The number of transplants can sometimes be increased by creating a series of donor exchanges, known as a chain, made of three or more incompatible pairs. A domino chain begins with a non-directed donor — a person who is not part of an incompatible pair, but selflessly wants to donate a kidney — and ends with a transplant for a recipient on the transplant waitlist who does not have a paired donor.

Launched in January 2009, the first surgeries from the LDPE program took place in June 2009.